Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      91 kDa including tags
    • Amino acids
      2 to 543

Associated products

Specifications

Our Abpromise guarantee covers the use of ab101504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The Specific activity of ab101504 was determined to be 185 nmol/min/mg.

  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Purity
    > 80 % Densitometry.
    The purity was determined to be >80% by densitometry
  • Form
    Liquid
  • Additional notes

    ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • c Yes
    • Cellular Yes 1 protein
    • Cellular Yes1 protein
    • HsT441
    • P61 YES
    • p61-Yes
    • Proto oncogene tyrosine protein kinase YES
    • Proto-oncogene c-Yes
    • Tyrosine-protein kinase Yes
    • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1
    • Viral oncogene yes 1 homolog 1
    • Viral oncogene yes1 homolog 1
    • Yamaguchi sarcoma oncogene
    • Yes
    • Yes 1
    • YES proto oncogene 1, Src family tyrosine kinase
    • YES_HUMAN
    • YES1
    • YES1 proto oncogene, Src family tyrosine kinase
    see all
  • Function
    Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab101504.
  • The Specific activity of ab101504 was determined to be 185 nmol/min/mg.

References

ab101504 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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