Recombinant Human ZAN protein (ab159808)

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SDS-PAGE - Recombinant Human ZAN protein (ab159808)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human ZAN protein

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        KEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADDEDWVRASG PSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQG

      • Amino acids

        19 to 113

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab159808 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • OTTHUMP00000211358
      • OTTHUMP00000211359
      • OTTHUMP00000211360
      • OTTHUMP00000211361
      • OTTHUMP00000211362
      • OTTHUMP00000211363
      • ZAN
      • ZAN_HUMAN
      • Zonadhesin
      see all

    • Function

      Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.

    • Tissue specificity

      In testis, primarily in haploid spermatids.

    • Sequence similarities

      Contains 1 EGF-like domain.
      Contains 3 MAM domains.
      Contains 4 TIL (trypsin inhibitory-like) domains.
      Contains 5 VWFC domains.
      Contains 4 VWFD domains.

    • Domain

      The MAM domains probably mediate sperm adhesion to the zona pellucida.
      During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
      The VWFD domain 2 may mediate covalent oligomerization.

    • Cellular localization

      Cell membrane. Exclusively on the apical region of the sperm head.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human ZAN protein (ab159808)
      SDS-PAGE - Recombinant Human ZAN protein (ab159808)
      ab159808 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab159808? Please let us know so that we can cite the reference in this datasheet.

    ab159808 has not yet been referenced specifically in any publications.

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