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Recombinant Human ZAN protein
Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
In testis, primarily in haploid spermatids.
Contains 1 EGF-like domain.
Contains 3 MAM domains. Contains 4 TIL (trypsin inhibitory-like) domains. Contains 5 VWFC domains. Contains 4 VWFD domains.
The MAM domains probably mediate sperm adhesion to the zona pellucida.
During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus. The VWFD domain 2 may mediate covalent oligomerization.
Cell membrane. Exclusively on the apical region of the sperm head.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"