Recombinant Human Zinc finger antiviral protein (ab153427)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human Zinc finger antiviral protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFV VLETGGEAGITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQ SERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEIC KSYKGEGRQQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLA IMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSR DRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLA SNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTR KGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKST SSGHREISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTT SSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFE HMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVV PFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE -
Amino acids
1 to 699 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab153427 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- ADP ribosyltransferase diphtheria toxin like 13
- ARTD13
- FLB6421
see all -
Function
Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication. -
Sequence similarities
Contains 4 C3H1-type zinc fingers.
Contains 1 PARP catalytic domain.
Contains 1 WWE domain. -
Domain
The second and fourth zinc fingers are involved in binding to specific viral RNAs. -
Cellular localization
Cytoplasm. Nucleus. Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab153427 has not yet been referenced specifically in any publications.