Description

  • Product name

    Recombinant Human Zhangfei protein
  • Purity

    > 85 % SDS-PAGE.
    ab183253 is purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAA AGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPD WHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQ RFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQAAT KSPRKAAAAA ARLNRLKKKE YVMGLESRVR GLAAENQELR AENRELGKRV QALQEESRYL RAVLANETGL ARLLSRLSGV GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVS VEFCSACARK ASSSLKM
    • Predicted molecular weight

      40 kDa including tags
    • Amino acids

      1 to 354
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_001034707.

Specifications

Our Abpromise guarantee covers the use of ab183253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 79% PBS, 20% Glycerol, 0.02% DTT, 0.002% PMSF

General Info

  • Alternative names

    • 1110034C16Rik
    • 6330417B10Rik
    • AI225749
    • AI606244
    • CREB/ATF bZIP transcription factor
    • Crebzf
    • FLJ94018
    • HCF-binding transcription factor Zhangfei
    • Host cell factor-binding transcription factor Zhangfei
    • LAZip
    • LAZipII
    • SHP-interacting leucine zipper protein
    • SMILE
    • ZF
    • ZHANG_HUMAN
    see all
  • Function

    Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
  • Tissue specificity

    In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
  • Sequence similarities

    Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
  • Cellular localization

    Nucleus. Colocalizes at punctate nuclear structures with CREB3 and HCFC1.
  • Information by UniProt

Images

  • 15% SDS PAGE analysis of ab183253 (3µg). 

References

ab183253 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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