Overview

  • Product name
    Recombinant Human ZKSCAN3 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      30 kDa
    • Amino acids
      175 to 440
    • Tags
      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127276 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names
    • dJ874C20.1
    • mszf35
    • SCAN-KRAB-zinc finger protein
    • Skz1
    • Zf47
    • Zfp-47
    • ZFP306
    • Zfp307
    • Zfp47
    • Zinc finger and SCAN domain containing protein 13
    • Zinc finger and SCAN domain-containing protein 13
    • Zinc finger protein 306
    • Zinc finger protein 306, isoform CRA_a
    • Zinc finger protein 307
    • Zinc finger protein 309
    • Zinc finger protein 47 homolog
    • Zinc finger protein with KRAB and SCAN domains 3
    • Zinc finger protein with KRAB and SCAN domains 3
    • Zinc finger protein zfp47
    • Zinc finger with KRAB and SCAN domains 3
    • ZKSC3_HUMAN
    • ZKSCAN3
    • ZNF309
    • ZSCAN13
    • ZSCAN35
    see all
  • Function
    Acts as a transcriptional regulator. Binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3'. Associates with chromatin at the ITGB4 and VEGF promoters. Activates the transcription of genes associated with colon cancer progression.
  • Tissue specificity
    Expressed in colorectal cancers (at protein level).
  • Sequence similarities
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 7 C2H2-type zinc fingers.
    Contains 1 KRAB domain.
    Contains 1 SCAN box domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab127276 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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