For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Recombinant Human ZNF354C protein
Full length protein
Amino Acid Sequence
MAVDLLSAQEPVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSSLVS LGIPFSMPKLIHQLQQGEDPCMVEREVPSDTRLGFKTWLETEALPHRQDI FIEETSQGMVKKESIKDGHWDINFEEAVEFESEIEEEQEKKPLRQMIDSH EKTISEDGNHTSLELGKSLFTNTALVTQQSVPIERIPNMYYTFGKDFKQN FDLMKCFQIYPGGKPHICNECGKSFKQNLHLIEHQRIHTGEKPYKCNECK KTFSHRSSLLSHQRIHTGEKPYKCNECEKAFSNSSTLIKHLRVHTGEKPY RCRECGKAFSQCSTLTVHQRIHTGEKLYKCGECEKAFNCRAKLHRHQRIH TGEKPYKCSECGKGYSQFTSLAEHQRFHTGEQLYTCLECGRTFTRIVTLI EHQRIHTGQKPYQCNECEKAFNQYSSFNEHRKIHTGEKLYTCEECGKAFG CKSNLYRHQRIHTGEKPYQCNQWKGLQPVFIFNRT
1 to 485
proprietary tag N-Terminus
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- and developmentally-regulated protein 3
May function as a transcription repressor. Suppresses osteogenic effects of RUNX2. Binds to 5'-CCACA-3' core sequence. May be involved in osteoblastic differentiation.
Expressed in kidney and skeletal muscle. Very low expression in brain and heart.
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 11 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Expressed in brain. Very low expression in lung and liver.
KRAB domain is not required for nuclear targeting or for DNA binding.
Zinc finger region is involved in nuclear targeting and DNA-binding.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"