Recombinant Human ZNF513 protein (ab165330)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human ZNF513 protein
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Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMPRRKQSHPQPVKCEGVKVDTEDSLDEGPGALVLESDLLLGQDLEFEEEE EEEEGDGNSDQLMGFERDSEGDSLGARPGLPYGLSDDESGGGRALSAESE VEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPLLPPRLLY SCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTH TGEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCGFRCCTPRPAR PPSPTEQEGAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLC GTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGGASG GPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHL DNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCN YSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAG GPGLSASEGWAPPHSPPSVLSSRGPPALGTAGSRAVHTDSS
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Amino acids1 to 541
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab165330 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- FLJ32203
- HMFT0656
- MGC105911
see all -
FunctionTranscriptional regulator that plays a role in retinal development and maintenance.
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Tissue specificityIn the retina, expressed in the outer and inner nuclear layers, and the ganglion cell layer.
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Involvement in diseaseDefects in ZNF513 are the cause of retinitis pigmentosa type 58 (RP58) [MIM:613617]. A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
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Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family.
Contains 8 C2H2-type zinc fingers. -
Cellular localizationNucleus.
- Information by UniProt
Images
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SDS-PAGE - Recombinant Human ZNF513 protein (ab165330)ab165330 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab165330 has not yet been referenced specifically in any publications.
