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  1. Link

    recombinant-human-znf513-protein-ab165330.pdf

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Epigenetics and Nuclear Signaling Transcription Domain Families Zinc Finger
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Recombinant Human ZNF513 protein (ab165330)

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  • SDS-PAGE - Recombinant Human ZNF513 protein (ab165330)
  • Datasheet
  • References
  • Protocols

Description

  • Product name

    Recombinant Human ZNF513 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MPRRKQSHPQPVKCEGVKVDTEDSLDEGPGALVLESDLLLGQDLEFEEEE EEEEGDGNSDQLMGFERDSEGDSLGARPGLPYGLSDDESGGGRALSAESE VEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPLLPPRLLY SCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTH TGEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCGFRCCTPRPAR PPSPTEQEGAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLC GTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGGASG GPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHL DNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCN YSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAG GPGLSASEGWAPPHSPPSVLSSRGPPALGTAGSRAVHTDSS
    • Amino acids

      1 to 541
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab165330 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • FLJ32203
    • HMFT0656
    • MGC105911
    • RP58
    • Zfp513
    • Zinc finger protein 513
    • ZN513_HUMAN
    • Znf513
    • Znf513 zinc finger protein 513
    see all
  • Function

    Transcriptional regulator that plays a role in retinal development and maintenance.
  • Tissue specificity

    In the retina, expressed in the outer and inner nuclear layers, and the ganglion cell layer.
  • Involvement in disease

    Defects in ZNF513 are the cause of retinitis pigmentosa type 58 (RP58) [MIM:613617]. A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similarities

    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 8 C2H2-type zinc fingers.
  • Cellular localization

    Nucleus.
  • Target information above from: UniProt accession Q8N8E2 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human ZNF513 protein (ab165330)
    SDS-PAGE - Recombinant Human ZNF513 protein (ab165330)
    ab165330 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Datasheets and documents

    • Datasheet
  • References

    ab165330 has not yet been referenced specifically in any publications.

    Publishing research using ab165330? Please let us know so that we can cite the reference in this datasheet.

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