Recombinant Human ZNF81 protein (ab166326)
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Overview
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Product nameRecombinant Human ZNF81 protein
See all ZNF81 proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMPANEDAPQPGEHGSACEVSVSFEDVTVDFSREEWQQLDSTQRRLYQDVM LENYSHLLSVGFEVPKPEVIFKLEQGEGPWTLEGEAPHQSCSDGKFGIKP SQRRISGKSTFHSEMEGEDTLC
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Amino acids1 to 122
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab166326 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- HFZ20
- Zinc finger protein 81
- ZNF81
- ZNF81_HUMAN
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FunctionMay be involved in transcriptional regulation.
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Involvement in diseaseDefects in ZNF81 are the cause of mental retardation X-linked type 45 (MRX45) [MIM:300498]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Note=A chromosomal aberration involving ZNF81 is found in a severe mental retardation patient. Translocation t(X;9)(p11.23;q34.3). -
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family.
Contains 12 C2H2-type zinc fingers.
Contains 1 KRAB domain. -
Cellular localizationNucleus.
- Information by UniProt
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Datasheets and documents
References
ab166326 has not yet been referenced specifically in any publications.