Name: Recombinant Human ZNF81 protein
SKU: ab166326

Product name

Recombinant Human ZNF81 protein
See all ZNF81 proteins and peptides
Protein length

Full length protein

Our Abpromise guarantee covers the use of ab166326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- HFZ20
- Zinc finger protein 81
- ZNF81
- ZNF81_HUMAN
Function

May be involved in transcriptional regulation.
Involvement in disease

Defects in ZNF81 are the cause of mental retardation X-linked type 45 (MRX45) [MIM:300498]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Note=A chromosomal aberration involving ZNF81 is found in a severe mental retardation patient. Translocation t(X;9)(p11.23;q34.3).
Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 12 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Cellular localization

Nucleus.
Target information above from: UniProt accession P51508 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human ZNF81 protein (ab166326)

ab166326 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab166326 has not yet been referenced specifically in any publications.

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Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Recombinant Human ZNF81 protein (ab166326)