The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
E3 ubiquitin protein ligase ZNRF1
E3 ubiquitin-protein ligase ZNRF1
Nerve injury gene 283
Nerve injury induced gene 283 protein
Nerve injury-induced gene 283 protein
Zinc and ring finger 1
zinc and ring finger protein 1
zinc finger and ring finger protein 1
Zinc/RING finger protein 1
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to substrates. May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin-protein ligase activity.
Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.
Protein modification; protein ubiquitination.
Contains 1 RING-type zinc finger.
The RING-type zinc finger domain is required for E3 ligase activity.
Endosome. Lysosome. Membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Associated with synaptic vesicle membranes in neurons.