Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKD KLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELK ATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRR AVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDGVFQKLGNLKQQAE QERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQS TGDTMGRDPGVSFKAVGLQPAGDVNLP
    • Molecular weight

      58 kDa including tags
    • Amino acids

      1 to 277
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab238344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituents: Tris buffer, 50% Glycerol

General Info

  • Alternative names

    • Human ZW10 interacting protein 1
    • HZwint 1
    • HZwint1
    • KNTC 2 AP
    • KNTC2AP
    • MGC 117174
    • MGC117174
    • ZW10 interacting kinetochore protein
    • ZW10 interacting protein 1
    • ZW10 interactor
    • ZW10 interactor, kinetochore protein
    • ZW10-interacting protein 1
    • ZWINT
    • ZWINT 1
    • Zwint-1
    • ZWINT_HUMAN
    • ZWINT1
    see all
  • Function

    Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
  • Cellular localization

    Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase.
  • Information by UniProt

Images

  • ab238344 analyzed by (Tris-Glycine gel) discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

References

ab238344 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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