Key features and details
- Expression system: Escherichia coli
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Product nameRecombinant mouse 4-1BBL protein (Fc Chimera)
See all 4-1BBL proteins and peptides
Expression systemEscherichia coli
Protein lengthProtein fragment
SequenceEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVV DVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWM SGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVT LTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEK KNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGKSGRTEPRPALTITTSPN LGTRENNADQVTPVSHIGCPNTTQQGSPVFAKLLAKNQASLCNTTLNWHS QDGAGSSYLSQGLRYEEDKKELVVDSPGLYYVFLELKLSPTFTNTGHKVQ GWVSLVLQAKPQVDDFDNLALTVELFPCSMENKLVDRSWSQLLLLKAGHR LSVGLRAYLHGAQDAYRDWELSYPNTTSFGLFLVKPDNPWE
Amino acids105 to 309
Additional sequence informationMouse Ig-Fc amino acid sequences are in Italics. Linker sequence (SGR) shown in bold. Mouse CD137L sequences are underlined.
Our Abpromise guarantee covers the use of ab72988 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 4 1BB L
- 4 1BB ligand
- 4 1BBL
FunctionCytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Tissue specificityExpressed in brain, placenta, lung, skeletal muscle and kidney.
Sequence similaritiesBelongs to the tumor necrosis factor family.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab72988 has not yet been referenced specifically in any publications.