The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL
< 1.000 Eu/µg
>95% by SDS-PAGE . Protein Content and Purity (typically = 95%) determined by: HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C long term. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full
recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be
further diluted to other aqueous solutions.
Activin beta A chain
Activin beta-A chain
Erythroid differentiation factor
Erythroid differentiation protein
Inhibin beta A chain
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.