Recombinant Mouse Annexin A1/ANXA1 protein (ab202184)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: MS, SDS-PAGE
Description
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Product name
Recombinant Mouse Annexin A1/ANXA1 protein
See all Annexin A1/ANXA1 proteins and peptides -
Purity
> 95 % SDS-PAGE.
ab202184 was purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMAMVSEFLKQARFLENQEQEYVQAVKS YKGGPGSAVSPYPSFNVSSDVAALHKAIMVKGVDEATIIDILTKRTNAQR QQIKAAYLQENGKPLDEVLRKALTGHLEEVVLAMLKTPAQFDADELRGAM KGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFR KALLALAKGDRCQDLSVNQDLADTDARALYEAGERRKGTDVNVFTTILTS RSFPHLRRVFQNYGKYSQHDMNKALDLELKGDIEKCLTTIVKCATSTPAF FAEKLYEAMKGAGTRHKALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAI LDETKGDYEKILVALCGGN -
Predicted molecular weight
41 kDa including tags -
Amino acids
1 to 346 -
Tags
His tag N-Terminus -
Additional sequence information
NP_034860.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab202184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Mass Spectrometry
SDS-PAGE
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 20% Glycerol (glycerin, glycerine), 0.02% DTT, 79% PBS
General Info
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Alternative names
- Annexin 1
- Annexin A1
- Annexin I
see all -
Function
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. -
Sequence similarities
Belongs to the annexin family.
Contains 4 annexin repeats. -
Domain
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
Post-translational
modificationsPhosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity. -
Cellular localization
Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab202184 has been referenced in 1 publication.
- Lee YJ et al. Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice. Biomolecules 12:N/A (2022). PubMed: 35327639