Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Mouse
    • Sequence

      AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
    • Molecular weight

      6 kDa
    • Amino acids

      21 to 71

Specifications

Our Abpromise guarantee covers the use of ab125748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Determined by the ability to chemoattract immature Human dendritic cells at a concentration of 10-100ng/ml.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity

    > 98 % SDS-PAGE.
    ab125748 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
  • Form

    Lyophilised
  • Additional notes

    Determined by the ability to chemoattract immature Human dendritic cells at a concentration of 10-100ng/ml.

    Previously labelled as beta 2 Defensin.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 7.40
    Constituent: 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    It is recommended to reconstitute ab125748 in sterile ultra pure water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab12574 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

General Info

  • Alternative names

    • BD 2
    • BD-2
    • BD2
    • beta 2
    • beta 2 Defensin
    • Beta defensin 2
    • Beta defensin 4B
    • Beta-defensin 2
    • Beta-defensin 4A
    • DEF B2
    • DEF B4
    • DEFB 102
    • DEFB 2
    • DEFB 4
    • DEFB102
    • DEFB2
    • DEFB2, formerly
    • DEFB4
    • DEFB4, formerly
    • DEFB4B
    • DEFB4P
    • Defensin
    • Defensin beta 2
    • Defensin, beta 4
    • Defensin, beta 4, pseudogene
    • Defensin, beta 4A
    • Defensin, beta 4B
    • Defensin, beta, 2, formerly
    • Defensin, beta, 4, formerly
    • DFB4A_HUMAN
    • HBD 2
    • hBD-2
    • HBD2
    • mBD-2
    • SAP 1
    • SAP1
    • Skin antimicrobial peptide 1
    • Skin-antimicrobial peptide 1
    see all
  • Function

    Has antibacterial activity.
  • Tissue specificity

    Expressed in the skin and respiratory tract.
  • Sequence similarities

    Belongs to the beta-defensin family. LAP/TAP subfamily.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab125748 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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