Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Mouse
    • Molecular weight

      9 kDa
    • Amino acids

      32 to 111

Specifications

Our Abpromise guarantee covers the use of ab129147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Determined by its ability to stimulate the proliferation of Mouse Balb/3T3 cells. The expected ED50 is = 0.01 ng/ml, corresponding to a specific activity of = 1 x 108 units/mg.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity

    > 98 % SDS-PAGE.
    Purity: > 98% by SDS-PAGE and HPLC anaylsis.
  • Form

    Lyophilised
  • Additional notes

    Endotoxin level: < 0.1 ng/µg.

    Protein previously labeled as Betacellulin.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstituted ab129147 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

General Info

  • Alternative names

    • Betacellulin
    • Betacellulin precursor
    • BTC
    • BTC_HUMAN
    • OTTHUMP00000160600
    • OTTHUMP00000219057
    • Probetacellulin
    see all
  • Function

    Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.
  • Tissue specificity

    Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
  • Sequence similarities

    Contains 1 EGF-like domain.
  • Cellular localization

    Cell membrane and Secreted > extracellular space.
  • Information by UniProt

References

ab129147 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab129147.
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