Bioactive grade

Recombinant mouse CXCL2 protein (Active) (ab243752)

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Description

  • Product name

    Recombinant mouse CXCL2 protein (Active)
    See all CXCL2 proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 1.0-10 ng/ml.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    P10889

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      AVVASELRCQCLKTLPRVDFKNIQSLSVTPPGPHCAQTEVIATLKGGQKV CLDPEAPLVQKIIQKILNKGKAN

    • Predicted molecular weight

      8 kDa

    • Amino acids

      28 to 100

    • Additional sequence information

      Full-length mature chain lacking the signal peptide.

Specifications

Our Abpromise guarantee covers the use of ab243752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

    HPLC

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: PBS

    0.2 µm filtered

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at =-20 °C. Further dilutions should be made in appropriate buffered solutions.

General Info

  • Alternative names

    • C-X-C motif chemokine 2
    • Chemokine (C X C motif) ligand 2
    • Chemokine, CXC motif, ligand 2
    • CINC 2a
    • CINC2a
    • CINC3
    • CXC chemokine
    • CXCL 2
    • Cxcl2
    • CXCL2_HUMAN
    • Cytokine-induced neutrophil chemoattractant 3
    • GRO 2
    • GRO b
    • GRO protein, beta
    • Gro-beta
    • GRO-beta(5-73)
    • GRO-beta-T
    • GRO2
    • GRO2 oncogene
    • GROb
    • GRObeta
    • Growth regulated protein beta
    • Growth-regulated protein beta
    • GROX
    • Hematopoietic synergistic factor
    • HSF
    • Macrophage inflammatory protein 2
    • Macrophage inflammatory protein 2 alpha
    • Macrophage inflammatory protein 2-alpha
    • Melanoma growth stimulatory activity beta
    • MGSA b
    • MGSA beta
    • MIP 2
    • MIP 2a
    • MIP2
    • MIP2 alpha
    • MIP2-alpha
    • MIP2A
    • MIP2alpha
    • SB-251353
    • Scyb
    • SCYB 2
    • SCYB2
    • Small inducible cytokine subfamily B, member 2
    see all

  • Function

    Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.

  • Sequence similarities

    Belongs to the intercrine alpha (chemokine CxC) family.

  • Post-translational
    modifications

    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant mouse CXCL2 protein (Active) (ab243752)
    SDS-PAGE - Recombinant mouse CXCL2 protein (Active) (ab243752)
    SDS-PAGE analysis of ab243752

References

ab243752 has not yet been referenced specifically in any publications.

Publishing research using ab243752? Please let us know so that we can cite the reference in this datasheet.

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