Bioactive grade

Recombinant mouse CXCL2 protein (Active) (ab243752)

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SDS-PAGE - Recombinant mouse CXCL2 protein (Active) (ab243752)

    Key features and details

    • Expression system: Escherichia coli
    • Endotoxin level: < 1.000 Eu/µg
    • Active: Yes
    • Suitable for: SDS-PAGE, Functional Studies, HPLC

    Description

    • Product name

      Recombinant mouse CXCL2 protein (Active)
      See all CXCL2 proteins and peptides

    • Biological activity

      Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 1.0-10 ng/ml.

    • Endotoxin level

      < 1.000 Eu/µg

    • Expression system

      Escherichia coli

    • Accession

      P10889

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Mouse

      • Sequence

        AVVASELRCQCLKTLPRVDFKNIQSLSVTPPGPHCAQTEVIATLKGGQKV CLDPEAPLVQKIIQKILNKGKAN

      • Predicted molecular weight

        8 kDa

      • Amino acids

        28 to 100

      • Additional sequence information

        Full-length mature chain lacking the signal peptide.

    Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab243752 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: PBS

        0.2 µm filtered

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at =-20 °C. Further dilutions should be made in appropriate buffered solutions.

      General Info

      • Alternative names

        • C-X-C motif chemokine 2
        • Chemokine (C X C motif) ligand 2
        • Chemokine, CXC motif, ligand 2
        • CINC 2a
        • CINC2a
        • CINC3
        • CXC chemokine
        • CXCL 2
        • Cxcl2
        • CXCL2_HUMAN
        • Cytokine-induced neutrophil chemoattractant 3
        • GRO 2
        • GRO b
        • GRO protein, beta
        • Gro-beta
        • GRO-beta(5-73)
        • GRO-beta-T
        • GRO2
        • GRO2 oncogene
        • GROb
        • GRObeta
        • Growth regulated protein beta
        • Growth-regulated protein beta
        • GROX
        • Hematopoietic synergistic factor
        • HSF
        • Macrophage inflammatory protein 2
        • Macrophage inflammatory protein 2 alpha
        • Macrophage inflammatory protein 2-alpha
        • Melanoma growth stimulatory activity beta
        • MGSA b
        • MGSA beta
        • MIP 2
        • MIP 2a
        • MIP2
        • MIP2 alpha
        • MIP2-alpha
        • MIP2A
        • MIP2alpha
        • SB-251353
        • Scyb
        • SCYB 2
        • SCYB2
        • Small inducible cytokine subfamily B, member 2
        see all

      • Function

        Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.

      • Sequence similarities

        Belongs to the intercrine alpha (chemokine CxC) family.

      • Post-translational
        modifications

        The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.

      • Cellular localization

        Secreted.
      • Information by UniProt

      Images

      • SDS-PAGE - Recombinant mouse CXCL2 protein (Active) (ab243752)
        SDS-PAGE - Recombinant mouse CXCL2 protein (Active) (ab243752)
        SDS-PAGE analysis of ab243752

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      References (0)

      Publishing research using ab243752? Please let us know so that we can cite the reference in this datasheet.

      ab243752 has not yet been referenced specifically in any publications.

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