Key features and details
- Expression system: Insect cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Product nameRecombinant mouse EPO protein (Fc Chimera)
See all EPO proteins and peptides
ED50 < 5 ng/ml as determined in a cell proliferation assay using Human TF-1 erythroleukemia cells.
Purity> 95 % SDS-PAGE.
ab170076 is purified by chromatography, sterile filtered and lyophilized.
Expression systemInsect cells
Protein lengthFull length protein
SequenceAPPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYA WKRMEVEEQAIEVWQGLSLLSEAILQAQALLANSSQPPETLQLHIDKAIS GLRSLTSLLRVLGAQKELMSPPDTTPPAPLRTLTVDTFCKLFRVYANFLR GKLKLYTGEVCRRGDR
Predicted molecular weight49 kDa
Amino acids27 to 192
Our Abpromise guarantee covers the use of ab170076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -80°C.
Constituent: 100% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionAdd 0.5ml deionized water. Aliquot and freeze unused portion.
- EPO alpha
RelevanceHuman erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab170076 has been referenced in 1 publication.
- Ferrao RD et al. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. Elife 7:N/A (2018). PubMed: 30044226