Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Mouse
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE
    • Molecular weight

      17 kDa including tags
    • Amino acids

      1 to 135
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab134630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 95 % SDS-PAGE.
    ab134630 was purified using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • 14 kDa laminin-binding protein
    • 14 kDa lectin
    • Beta galactoside binding lectin
    • Beta galactoside binding lectin L 14 I
    • beta galactoside binding protein
    • Beta-galactoside-binding lectin L-14-I
    • DKFZp686E23103
    • Gal 1
    • Gal-1
    • GAL1
    • Galaptin
    • Galbp
    • Galectin
    • Galectin-1
    • Galectin1
    • GBP
    • HBL
    • HLBP14
    • HPL
    • L 14.5
    • L-14.5
    • L14
    • Lactose binding lectin 1
    • Lactose-binding lectin 1
    • Lect14
    • Lectin galactoside binding soluble 1
    • Lectin galactoside-binding soluble 1
    • LEG1_HUMAN
    • LGALS 1
    • LGALS1
    • Lgals1 lectin galactose binding soluble 1
    • MAPK activating protein MP12
    • Putative MAPK activating protein MP12
    • Putative MAPK-activating protein PM12
    • S Lac lectin 1
    • S-Lac lectin 1
    see all
  • Function

    May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.
  • Tissue specificity

    Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
  • Sequence similarities

    Contains 1 galectin domain.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab134630 (3µg)

References

ab134630 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abreviews
Application
Other
We tested to see if the His-tag interfered with hemagglutination. We were not able to show agglutination even after the addition of DTT.

Abcam user community

Verified customer

Submitted Jan 11 2019

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