Overview

Description

  • Nature

    Recombinant
  • Source

    Insect cells
  • Amino Acid Sequence
    • Accession
    • Species

      Mouse
    • Molecular weight

      79 kDa
    • Amino acids

      33 to 728

Specifications

Our Abpromise guarantee covers the use of ab129134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Determined by the dose-dependent stimulation of the proliferation of Mouse IMCD3 cells using a concentration range of 10-20 ng/ml.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity

    > 95 % SDS-PAGE.
    Purity: > 95% by SDS-PAGE and HPLC anaylsis.
  • Form

    Lyophilised
  • Additional notes

    Endotoxin level: < 0.1 ng/µg of HGF.
    Please note: always centrifuge product before opening Vial. Determined by the dose-dependent stimulation of the proliferation of Mouse IMCD3 cells using a concentration range of 10-20 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    pH: 7.2
    Constituent: Tris buffer

    10 mM Tris + 100 mM L-Arginine + 200 mM NaCl.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstituted ab129134 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

General Info

  • Alternative names

    • DFNB39
    • F TCF
    • Fibroblast derived tumor cytotoxic factor
    • Hepatocyte growth factor
    • Hepatocyte growth factor (hepapoietin A; scatter factor)
    • Hepatocyte growth factor beta chain
    • Hepatocyte growth factor precursor
    • Hepatopoietin A
    • Hepatopoietin-A
    • Hgf
    • HGF_HUMAN
    • HGFB
    • HPTA
    • Lung fibroblast derived mitogen
    • OTTHUMP00000161349
    • OTTHUMP00000206710
    • OTTHUMP00000206711
    • OTTHUMP00000206712
    • OTTHUMP00000206713
    • OTTHUMP00000206730
    • Scatter factor
    • SF
    see all
  • Function

    Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
  • Involvement in disease

    Deafness, autosomal recessive, 39
  • Sequence similarities

    Belongs to the peptidase S1 family. Plasminogen subfamily.
    Contains 4 kringle domains.
    Contains 1 PAN domain.
    Contains 1 peptidase S1 domain.
  • Information by UniProt

References

ab129134 has not yet been referenced specifically in any publications.

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