Description

  • Product name

    Recombinant mouse IL-11 protein
    See all IL-11 proteins and peptides
  • Biological activity

    Specific activity of 5 x 105 units/mg.
  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • Endotoxin level

    < 0.100 Eu/µg
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      M -PGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
    • Amino acids

      22 to 199

Specifications

Our Abpromise guarantee covers the use of ab69654 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8oC for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20oC to -80oC.

General Info

  • Alternative names

    • Adipogenesis inhibitory factor
    • AGIF
    • IL 11
    • IL-11
    • Il11
    • IL11_HUMAN
    • Interleukin 11
    • Interleukin-11
    • Oprelvekin
    see all
  • Function

    Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
  • Sequence similarities

    Belongs to the IL-6 superfamily.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

This product has been referenced in:

  • Crist SA  et al. Nuclear factor of activated T cells (NFAT) mediates CD154 expression in megakaryocytes. Blood 111:3553-61 (2008). Read more (PubMed: 18180380) »
See 1 Publication for this product

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