Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
- High batch-to-batch consistency
- Optimal bioactivity
- Guaranteed identical to human native proteins
- >95% purity
- Ultra-low endotoxin levels: <0.005 Eu/µg
- Carrier and tag free
Product nameRecombinant mouse IL-22 protein
See all IL-22 proteins and peptides
Determined by its ability to induce STAT3 activation in COLO 205 cells. The expected ED50 for this effect is 150-400 pg/ml.
Purity> 98 % SDS-PAGE.
Purity is greater than 98% by SDS-PAGE gel and HPLC analyses.
Expression systemEscherichia coli
Protein lengthFull length protein
SequenceMLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV
Our Abpromise guarantee covers the use of ab84083 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesEndotoxin level is less than 0.1 ng per µg (1EU/µg).
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstituted ab84083 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20oC. Avoid repeated freeze/thaw cycles.
- Cytokine Zcyto18
- IL 10 related T cell derived inducible factor
- IL 21
FunctionCytokine that contributes to the inflammatory response in vivo.
Sequence similaritiesBelongs to the IL-10 family.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab84083 has been referenced in 2 publications.
- Stritesky GL et al. IL-23 promotes maintenance but not commitment to the Th17 lineage. J Immunol 181:5948-55 (2008). PubMed: 18941183
- Kreymborg K et al. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol 179:8098-104 (2007). PubMed: 18056351