Bioactive grade

Recombinant mouse IL36 beta/IL-1F8 protein (Active) (ab241515)

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Description

  • Product name

    Recombinant mouse IL36 beta/IL-1F8 protein (Active)
    See all IL36 beta/IL-1F8 proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0x105 IU/mg.

  • Purity

    > 97 % SDS-PAGE.
    > 97 % by HPLC.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    Q9D6Z6

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      SSQSPRNYRVHDSQQMVWVLTGNTLTAVPASNNVKPVILSLIACRDTEFQ DVKKGNLVFLGIKNRNLCFCCVEMEGKPTLQLKEVDIMNLYKERKAQKAF LFYHGIEGSTSVFQSVLYPGWFIATSSIERQTIILTHQRGKLVNTNFYIE SEK

    • Predicted molecular weight

      17 kDa

    • Amino acids

      31 to 183

    • Additional sequence information

      This product is the mature full length protein from aa 31 to 183. The propeptide is not included.

Specifications

Our Abpromise guarantee covers the use of ab241515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: PBS, 5% Trehalose

    0.2 µm filtered.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at = -20 °C. Further dilutions should be made in appropriate buffered solutions.

General Info

  • Alternative names

    • 2310043N20Rik
    • Family of interleukin 1 eta
    • FIL1
    • FIL1 (ETA)
    • FIL1 eta
    • FIL1H
    • FILI-(ETA)
    • IL 1F8
    • IL 1F8 (FIL1 eta
    • IL 1H2
    • IL-1 eta
    • IL-1F8
    • IL-1H2
    • IL1 ETA
    • IL1F8
    • IL1F8 (Canonical product IL 1F8a)
    • IL1F8_HUMAN
    • IL1H2
    • IL36 beta
    • IL36B
    • Interleukin 1 family, member 8
    • Interleukin 1 family, member 8 (eta)
    • Interleukin 1 homolog 2
    • Interleukin 1 Superfamily e
    • Interleukin 36 beta
    • Interleukin-1 eta
    • Interleukin-1 family member 8
    • Interleukin-1 homolog 2
    • MGC126880
    • MGC126882
    • OTTMUSP00000012797
    • RP23-176J12.1
    see all

  • Tissue specificity

    Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in other tissues or in any hematopoietic cell lines.

  • Sequence similarities

    Belongs to the IL-1 family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant mouse IL36 beta/IL-1F8 protein (Active) (ab241515)
    SDS-PAGE - Recombinant mouse IL36 beta/IL-1F8 protein (Active) (ab241515)

    SDS-PAGE analysis of ab241515.

References

ab241515 has not yet been referenced specifically in any publications.

Publishing research using ab241515? Please let us know so that we can cite the reference in this datasheet.

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