Recombinant Mouse PD-L1 protein (Fc Chimera) (Biotin) (ab216261)

Description

  • Product name

    Recombinant Mouse PD-L1 protein (Fc Chimera) (Biotin)
    See all PD-L1 proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    >90% purity as measured by gel filtration.
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      AFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQF VAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIIS YGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWT NSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQ NHTAELIIPELPATHPPQNRT
    • Predicted molecular weight

      54 kDa including tags
    • Amino acids

      18 to 238
    • Tags

      Avi tag C-Terminus
    • Additional sequence information

      Fused at the C-terminus to the Fc portion of mouse IgG2a (NM_021893). Biotinylated using AviTag technology.
  • Conjugation

    Biotin

Specifications

Our Abpromise guarantee covers the use of ab216261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol, 79% Phosphate Buffer

General Info

  • Alternative names

    • B7 H
    • B7 H1
    • B7 homolog 1
    • B7-H1
    • B7H
    • B7H1
    • CD 274
    • CD274
    • CD274 antigen
    • CD274 molecule
    • MGC142294
    • MGC142296
    • OTTHUMP00000021029
    • PD L1
    • PD-L1
    • PD1L1_HUMAN
    • PDCD1 ligand 1
    • PDCD1L1
    • PDCD1LG1
    • PDL 1
    • PDL1
    • Programmed cell death 1 ligand 1
    • Programmed death ligand 1
    • RGD1566211
    see all
  • Function

    Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
  • Tissue specificity

    Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane and Endomembrane system.
  • Information by UniProt

Images

  • 4-20% SDS-PAGE analysis of 3 μg ab216261.

    This protein runs at an apparent higher molecular weight due to glycosylation.

  • Gel filtration curve of ab216261.

References

ab216261 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab216261.
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