Recombinant Mouse PSCA protein (His tag) (ab241245)

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SDS-PAGE - Recombinant Mouse PSCA protein (His tag) (ab241245)

    Key features and details

    • Expression system: Yeast
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Mouse PSCA protein (His tag)
      See all PSCA proteins and peptides

    • Purity

      > 90 % SDS-PAGE.

    • Expression system

      Yeast

    • Accession

      P57096

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Mouse

      • Sequence

        LQCYSCTAQMNNRDCLNVQNCSLDQHSCFTSRIRAIGLVTVISKGCSSQC EDDSENYYLGKKNITCCYSDLCNVN

      • Predicted molecular weight

        10 kDa including tags

      • Amino acids

        21 to 95

      • Tags

        His tag N-Terminus

      • Additional sequence information

        Full length mature chain without signal peptide, without propeptide.

    Specifications

    Our Abpromise guarantee covers the use of ab241245 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • PRO 232
      • PRO232
      • Prostate stem cell antigen

    • Relevance

      PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

    • Cellular localization

      Cell membrane; Lipid-anchor, GPI-anchor.

    Images

    • SDS-PAGE - Recombinant Mouse PSCA protein (His tag) (ab241245)
      SDS-PAGE - Recombinant Mouse PSCA protein (His tag) (ab241245)

      (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab241245.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab241245? Please let us know so that we can cite the reference in this datasheet.

    ab241245 has not yet been referenced specifically in any publications.

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