Recombinant Mouse SLAMF7/CS1 protein (His tag) (ab235972)
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Description
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Product name
Recombinant Mouse SLAMF7/CS1 protein (His tag)
See all SLAMF7/CS1 proteins and peptides -
Purity
> 85 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
SGTLKKVAGALDGSVTFTLNITEIKVDYVVWTFNTFFLAMVKKDGVTSQS SNKERIVFPDGLYSMKLSQLKKNDSGAYRAEIYSTSSQASLIQEYVLHVY KHLSRPKVTIDRQSNKNGTCVINLTCSTDQDGENVTYSWKAVGQGDNQFH DGATLSIAWRSGEKDQALTCMARNPVSNSFSTPVFPQKLCEDAATDLTSL RG -
Predicted molecular weight
28 kDa including tags -
Amino acids
23 to 224 -
Tags
His tag N-Terminus -
Additional sequence information
N-terminal 6xHis-tagged.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab235972 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
This product was previously labelled as SLAMF7
This product was previously labelled as SLAMF7
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: Tris buffer, 50% Glycerol
General Info
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Alternative names
- 19A
- 19A24 protein
- CD 319
see all -
Relevance
SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms. -
Cellular localization
Membrane; Single-pass type I membrane protein.
Images
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SDS-PAGE - Recombinant Mouse SLAMF7/CS1 protein (His tag) (ab235972)(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab235972.
Datasheets and documents
References
ab235972 has not yet been referenced specifically in any publications.
