Overview

  • Product name

    Recombinant Mycobacterium tuberculosis ESAT6 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Baculovirus
  • Amino Acid Sequence
    • Accession
    • Species

      Mycobacterium tuberculosis
    • Sequence

      ADPMTEQQWN FAGIEAAASA IQGNVTSIHS LLDEGKQSLT KLAAAWGGSG SEAYQGVQQK WDATATELNN ALQNLARTIS EAGQAMASTE GNVTGMFAHH HHHH
    • Molecular weight

      11 kDa including tags
    • Amino acids

      1 to 95
    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.
    ab124574 is purified using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • 6 kDa early secretory antigenic target
    • 6 kDa early secretory antigenic target ESXA
    • ESAT 6
    • esaT6
    • ESXA
    see all
  • Relevance

    The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response.
  • Cellular localization

    Secreted

Images

  • 15% SDS-PAGE showing ab124574 at approximately 11kDa (3µg).

References

This product has been referenced in:

  • Sepulveda D  et al. Bioelectrochemical Detection of Mycobacterium tuberculosis ESAT-6 in an Antibody-Based Biomicrosystem. Sensors (Basel) 17:N/A (2017). Read more (PubMed: 28937645) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for contacting us.

ab124574 is a recombinant full length mycobacterium tuberculosis ESAT6 expressed by Baculovirus and purified by using conventional chromatography.


I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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