The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The biological activity of ab87693 was measured in a cell proliferation assay using the human TF1 cell line. The ED50 for this effect is typically 250 - 375 ng/mL.
% SDS-PAGE. ab87693 is purified by Ion-exchange chromatography.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Constituents: 2.68% PBS, 10% Trehalose
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.