Overview

Description

  • Nature

    Recombinant
  • Source

    Yeast
  • Amino Acid Sequence
    • Accession
    • Species

      Rabbit
    • Sequence

      SDGGAQDCCL KYSLRKIPHK VVRSYRKQEP SLGCPISAIL FSPRKRSQPE LCADPKEPWV QQLMKRLDRP PAPKKQVQAC RKDGGASKSG KKGKGCKRTE QPQTPKGP
    • Molecular weight

      12 kDa
    • Amino acids

      4 to 111
    • Additional sequence information

      Entrez gene: 100144337. Produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specifications

Our Abpromise guarantee covers the use of ab208811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Form

    Lyophilised
  • Additional notes

    seq 100% homologue to unreviewed swissprot, that i have entered in peptide page as entrez gene code link does not work in preview page (that by default sends to to swissprot).

    It can be used in cell culture, as an CCL21 ELISA Standard, and as a Western Blot Control.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.

    Constituents: 90% PBS, 10% Trehalose

  • Reconstitution
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

General Info

  • Alternative names

    • 6Ckine
    • Beta chemokine exodus 2
    • Beta-chemokine exodus-2
    • C C motif chemokine ligand 21
    • C-C motif chemokine 21
    • CCL21
    • CCL21_HUMAN
    • Chemokine (C-C motif) ligand 21
    • Chemokine CC motif ligand 21
    • CKb9
    • ECL
    • Efficient Chemoattractant for Lymphocytes
    • SCYA21
    • Secondary lymphoid tissue chemokine
    • Secondary lymphoid-tissue chemokine
    • SLC
    • Small inducible cytokine A21
    • Small inducible cytokine subfamily A (Cys-Cys), member 21
    • Small-inducible cytokine A21
    • TCA4
    • UNQ784/PRO1600
    see all
  • Function

    Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
  • Tissue specificity

    Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab208811 has not yet been referenced specifically in any publications.

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