Recombinant Rabbit IL-8 protein (ab222165)

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Key features and details

  • Expression system: Yeast
  • Purity: > 95% Ion Exchange Chromatography
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Rabbit IL-8 protein
    See all IL-8 proteins and peptides

  • Purity

    > 95 % Ion Exchange Chromatography.

  • Expression system

    Yeast

  • Accession

    P19874

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Rabbit

    • Sequence

      AVLTRIGTELRCQCIKTHSTPFHPKFIKELRVIESGPHCANSEIIVKLVD GRELCLDPKEKWVQKVVQIFLKRAEQQES

    • Predicted molecular weight

      9 kDa

    • Amino acids

      23 to 101

    • Additional sequence information

      This product is the mature full length protein from aa 23 to 101. The signal peptide is not included.

Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab222165 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C long term. Avoid freeze / thaw cycle. Stable for 12 months at -20°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

      Constituents: PBS, 10% Trehalose

    • Reconstitution
      Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

    General Info

    • Alternative names

      • (Ala-IL-8)77
      • (Ser-IL-8)72
      • 9E3
      • Beta thromboglobulin like protein
      • C-X-C motif chemokine 8
      • CEF-4
      • chemokine, CXC motif, ligand 8
      • CXCL8
      • Emoctakin
      • GCP-1
      • GCP/IL-8 protein I
      • GCP/IL-8 protein II
      • GCP/IL-8 protein III
      • GCP/IL-8 protein IV
      • GCP/IL-8 protein V
      • GCP/IL-8 protein VI
      • GCP1
      • Granulocyte chemotactic protein 1
      • IL-8
      • IL-8(1-77)
      • IL-8(9-77)
      • IL8
      • IL8/NAP1 form I
      • IL8/NAP1 form II
      • IL8/NAP1 form III
      • IL8/NAP1 form IV
      • IL8/NAP1 form V
      • IL8/NAP1 form VI
      • IL8_HUMAN
      • Inteleukin 8
      • LECT
      • LUCT
      • Lymphocyte-derived neutrophil-activating factor
      • LYNAP
      • MDNCF
      • MDNCF-b
      • MDNCF-c
      • MONAP
      • Monocyte derived neutrophil activating peptide
      • Monocyte derived neutrophil chemotactic factor
      • Monocyte-derived neutrophil chemotactic factor
      • Monocyte-derived neutrophil-activating peptide
      • NAF
      • NAP 1
      • NAP-1
      • NAP1
      • Neutrophil activating peptide 1
      • Neutrophil activating protein 1
      • Neutrophil-activating factor
      • Neutrophil-activating protein 1
      • Protein 3 10C
      • Protein 3-10C
      • SCYB 8
      • SCYB8
      • Small inducible cytokine subfamily B member 8
      • T cell chemotactic factor
      • T-cell chemotactic factor
      • TSG 1
      • TSG1
      see all

    • Function

      IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.

    • Post-translational
      modifications

      Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab222165? Please let us know so that we can cite the reference in this datasheet.

    ab222165 has not yet been referenced specifically in any publications.

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