Description

  • Product name

    Recombinant rat Activin A protein
    See all Activin A proteins and peptides
  • Biological activity

    The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL.
  • Purity

    >= 95 % SDS-PAGE.
    ab151689 is >95% pure as determined by HPLC, Reducing and Non-reducing SDS-PAGE.
  • Endotoxin level

    <=1.000 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Rat
    • Sequence

      MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
    • Predicted molecular weight

      26 kDa
    • Amino acids

      309 to 424

Specifications

Our Abpromise guarantee covers the use of ab151689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

    Functional Studies

  • Form

    Lyophilised
  • Additional notes

    This product shares 100% homology with amino acids 309 - 424 of Mouse Activin A and amino acids 311 - 426 of Human Activin A. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituent: 0.02% Trifluoroacetic acid

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be further diluted to other aqueous solutions. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.

General Info

  • Alternative names

    • Activin A
    • Activin beta A chain
    • Activin beta-A chain
    • ActivinA
    • EDF
    • Erythroid differentiation factor
    • Erythroid differentiation protein
    • follicle stimulating hormone releasing protein
    • FRP
    • FSH releasing factor
    • FSH releasing protein
    • INHBA
    • INHBA_HUMAN
    • Inhibin beta A
    • Inhibin beta A chain
    • Inhibin beta A subunit
    see all
  • Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • Functional analysis of ab151689
  • SDS PAGE analysis of ab151689 under non-reducing (-) and reducing (+) conditions. Stained with Coomassie Blue.

References

ab151689 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151689.
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