Recombinant Rat IL-1RA protein (ab201897)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
-
Product name
Recombinant Rat IL-1RA protein
See all IL-1RA proteins and peptides -
Purity
> 90 % SDS-PAGE.
purified by using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Rat -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSHPAGKRPCKMQAFRIWDTNQKTFYLRN NQLIAGYLQGPNTKLEEKIDMVPIDFRNVFLGIHGGKLCLSCVKSGDDTK LQLEEVNITDLNKNKEEDKRFTFIRSETGPTTSFESLACPGWFLCTTLEA DHPVSLTNTPKEPCTVTKFYFQEDQ -
Predicted molecular weight
20 kDa including tags -
Amino acids
27 to 178 -
Tags
His tag N-Terminus -
Additional sequence information
Mature protein without signal peptide.
-
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab201897 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
-
Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.02% DTT, 89% PBS, 10% Glycerol (glycerin, glycerine)
General Info
-
Alternative names
- DIRA
- F630041P17Rik
- ICIL 1RA
see all -
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. -
Tissue specificity
The intracellular form of IL1RN is predominantly expressed in epithelial cells. -
Involvement in disease
Microvascular complications of diabetes 4
Interleukin 1 receptor antagonist deficiency -
Cellular localization
Cytoplasm and Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab201897 has not yet been referenced specifically in any publications.