Bioactive grade

Recombinant rat IP10 protein (Active) (ab243765)

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SDS-PAGE - Recombinant rat IP10 protein (Active) (ab243765)

    Key features and details

    • Expression system: Escherichia coli
    • Endotoxin level: < 1.000 Eu/µg
    • Active: Yes
    • Suitable for: Functional Studies, HPLC, SDS-PAGE

    Description

    • Product name

      Recombinant rat IP10 protein (Active)
      See all IP10 proteins and peptides

    • Biological activity

      Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR3 transfected HEK-293 cells is in a concentration range of 10-50 ng/ml.

    • Endotoxin level

      < 1.000 Eu/µg

    • Expression system

      Escherichia coli

    • Accession

      P48973

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Rat

      • Sequence

        IPLARTVRCTCIDFHEQPLRPRAIGKLEIIPASLSCPHVEIIATMKKNNE KRCLNPESEAIKSLLKAVSQRRSKRAP

      • Predicted molecular weight

        9 kDa

      • Amino acids

        22 to 98

      • Additional sequence information

        Full length mature chain without signal peptide.

    Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab243765 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        HPLC

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: PBS

        0.2 µm filtered

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20degC. Further dilutions should be made in appropriate buffered solutions.

      General Info

      • Alternative names

        • Interferon gamma induced factor MOB1, mouse, homolog of
        • Interferon gamma induced protein 10
        • 10 kDa interferon gamma induced protein
        • 10 kDa interferon gamma-induced protein
        • C X C motif chemokine 10
        • C7
        • Chemokine (C X C motif) ligand 10
        • Chemokine CXC motif ligand 10
        • Crg 2
        • CRG2
        • CXCL10
        • CXCL10(1-73)
        • CXL10_HUMAN
        • Gamma IP10
        • Gamma-IP10
        • gIP 10
        • GIP10
        • IFI10
        • INP 10
        • INP10
        • Interferon activated gene 10
        • Interferon gamma induced cell line
        • Interferon inducible cytokine IP 10
        • Interferon inducible cytokine IP10
        • IP 10
        • IP-10
        • Mob 1
        • MOB1
        • Protein 10 from interferon (gamma) induced cell line
        • SCYB10
        • Small inducible cytokine B10
        • Small inducible cytokine B10 precursor
        • Small inducible cytokine subfamily B (Cys X Cys) member 10
        • Small inducible cytokine subfamily B CXC member 10
        • Small inducible cytokine subfamily B, member 10
        • Small-inducible cytokine B10
        see all

      • Function

        Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.

      • Sequence similarities

        Belongs to the intercrine alpha (chemokine CxC) family.

      • Post-translational
        modifications

        CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.

      • Cellular localization

        Secreted.
      • Information by UniProt

      Images

      • SDS-PAGE - Recombinant rat IP10 protein (Active) (ab243765)
        SDS-PAGE - Recombinant rat IP10 protein (Active) (ab243765)
        SDS Page analysis of IP10 with ab243765.

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      References (0)

      Publishing research using ab243765? Please let us know so that we can cite the reference in this datasheet.

      ab243765 has not yet been referenced specifically in any publications.

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