The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological Activity: Induces proliferation of BAF/3 cells stably transfected with the long form of Human leptin receptor.
< 0.100 Eu/µg
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Preparation and Storage
Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituent: 0.36% Sodium bicarbonate
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitute with sterile water or 0.4% sodium bicarbonate to 0.5-1.0mg/ml, pH 8-9. Never vortex. Do not reconstitute to less than 0.1mg/ml. Further dilutions should be made with medium containing a carrier protein (BSA or HSA 0.1%) and filter sterilized.
Leptin (murine obesity homolog)
Leptin (obesity homolog, mouse)
Leptin Murine Obesity Homolog
Leptin Precursor Obesity Factor
Obese, mouse, homolog of
Obesity homolog mouse
Obesity Murine Homolog Leptin
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Involvement in disease
Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.