Recombinant Rat Leptin protein (ab646)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Rat
    • Sequence
      Rat Leptin is a 16.2 kDa protein containing 147 amino acid residues: MVPIHKVQDD TKTLIKTIVT RINDISHTQS VSARQRVTGL DFIPGLHPIL SLSKM DQTLAVYQQILTSLP SQNVLQIAHD LENLRDLLHL LAFSKSCSLP Q TRGLQKPES LDGVLEASLYSTEVVALSRL QGSLQDILQQ LDLSPEC

Specifications

Our Abpromise guarantee covers the use of ab646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    n/a

  • Reconstitution
    Reconstitute with 1ml pure water.

General Info

  • Alternative names
    • FLJ94114
    • LEP
    • LEP_HUMAN
    • LEPD
    • Leptin
    • Leptin (murine obesity homolog)
    • Leptin (obesity homolog, mouse)
    • Leptin Murine Obesity Homolog
    • Leptin Precursor Obesity Factor
    • OB
    • Obese protein
    • Obese, mouse, homolog of
    • Obesity
    • Obesity factor
    • Obesity homolog mouse
    • Obesity Murine Homolog Leptin
    • OBS
    • OTTHUMP00000212285
    see all
  • Function
    May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
  • Involvement in disease
    Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • Sequence similarities
    Belongs to the leptin family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab646 has not yet been referenced specifically in any publications.

Publishing research using ab646? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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Question

What is the buffer constituants of the solution the protein is in before lyophilizing? Doing mass spec and need to make a compatable buffer.

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Answer

Thank you for calling Abcam.

The lot of Rat Leptin that you received was lyophilized from 10mM Sodium Citrate, pH 4.0.

Please let me know if you have any additional questions.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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