Bioactive grade

Recombinant rhesus monkey GM-CSF protein (Active) (ab243115)

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Description

  • Product name

    Recombinant rhesus monkey GM-CSF protein (Active)
    See all GM-CSF proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of >1.0x107 IU/mg.

  • Purity

    > 98 % SDS-PAGE.
    > 98 % by HPLC.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    Q9GL44

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Rhesus monkey

    • Sequence

      APARSPSPGTQPWEHVNAIQEARRLLNLSRDTAAEMNKTVEVVSEMFDLQ EPSCLQTRLELYKQGLQGSLTKLKGPLTMMASHYKQHCPPTPETSCATQI ITFQSFKENLKDFLLVIPFDCWEPVQE

    • Predicted molecular weight

      16 kDa

    • Amino acids

      18 to 144

    • Additional sequence information

      This product is the mature full length protein from aa 18 to 144. The signal peptide is not included.

Specifications

Our Abpromise guarantee covers the use of ab243115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: PBS

    0.2 µm filtered.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20 °C or below. Further dilutions should be made in appropriate buffered solutions.

General Info

  • Alternative names

    • Colony stimulating factor
    • Colony Stimulating Factor 2
    • Colony stimulating factor 2 (granulocyte-macrophage)
    • Colony-stimulating factor
    • CSF
    • CSF 2
    • CSF2
    • CSF2_HUMAN
    • GM-CSF
    • GMCSF
    • Granulocyte Macrophage Colony Stimulating Factor
    • Granulocyte-macrophage colony-stimulating factor
    • MGC131935
    • MGC138897
    • MGI1GM
    • Molgramostin
    • Pluripoietin-a
    • Sargramostim
    see all

  • Function

    Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

  • Sequence similarities

    Belongs to the GM-CSF family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant rhesus monkey GM-CSF protein (Active) (ab243115)
    SDS-PAGE - Recombinant rhesus monkey GM-CSF protein (Active) (ab243115)
    SDS Page analysis of ab243115

References

ab243115 has not yet been referenced specifically in any publications.

Publishing research using ab243115? Please let us know so that we can cite the reference in this datasheet.

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