Product nameRecombinant Rubella Virus capsid protein
See all Rubella Virus capsid proteins and peptides
Purity> 90 % SDS-PAGE.
Purified by ultracentifugation.
Expression systemSaccharomyces cerevisiae
Protein lengthFull length protein
Our Abpromise guarantee covers the use of ab74574 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C.
ReconstitutionReconstitute with PBS or 8M urea (to obtain 0.5 mg/ml protein stock solution). After reconstitution in PBS store at -20°C. Avoid freeze / thaw cycles. Proteins reconstituted in 8M urea store at 4°C.
- Coat protein
- rubella capsid
- Structural polyprotein
RelevanceRubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It causes German measles ( a mild contagious eruptive disease, capable of producing congenital defects in infants born to mothers infected during the first three months of pregnancy). Rubella virus is an enveloped positive-strand RNA virus. The genome encodes two open reading frames (ORFs): the 5'-proximal ORF encodes viral nonstructural proteins (NSP) that are responsible for viral genome replication, while the 3'-proximal ORF encodes three virion structural proteins (SP), the capsid protein (CP), and the two envelope glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.
Cellular localizationCytoplasmic in host cells concentrated around Golgi region and mitochondrion.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab74574 has been referenced in 2 publications.
- Martinez DR et al. Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women. Cell 178:190-201.e11 (2019). PubMed: 31204101
- Sun AC et al. High-Density Redox Amplified Coulostatic Discharge-Based Biosensor Array. IEEE J Solid-State Circuits 53:2054-2064 (2018). PubMed: 30559530