Description

  • Product name

    Recombinant West Nile Virus preM protein
    See all West Nile Virus preM proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Additional sequence information

      Tagged with six histidines.

Specifications

Our Abpromise guarantee covers the use of ab49049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituent: 0.0536% PBS

General Info

  • Alternative names

    • membrane glycoprotein M
    • membrane glycoprotein precursor prM
    • pre M protein
    • West Nile virus
  • Relevance

    West Nile Virus is part of the flavivirus family, many of which are capable of causing serious illness in humans. The ssRNA + strand virus is enveloped and spherical with a diameter of 40-50 nm, similar to all flaviviruses. The virion of this virus is a nucleocapsid covered by a lipoprotein envelope. The envelope contains two proteins: the protein M and glycoprotein E. The nucleocapsid is a complex of protein C and mRNA. In immature particles, there are 60 icosaedrally organized trimeric spikes on the surface. Each spike consists of three heterodimers of envelope protein M precursor (prM) and envelope protein E. Inside cells, viral particles will contain a preM particle and E in a complex that matures through proteolytic cleavage and processing in the Golgi apparatus. WNV has three different effects on humans, the first is asymptomatic infection; the second is a mild febrile syndrome termed West Nile Fever; the third is a neuroinvasive disease termed West Nile meningitis or encephalitis. In infected individuals the ratio between the three states is roughly 110:30:1. The main route of human infection is through the bite of an infected mosquito.

References

ab49049 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Answer

Thank you for contacting us. Because we carry over 70,000 products, it isn't feasible for us to keep small sample sizes of our products.

We are happy to reassure our customers that all of our products are covered by our Abpromise, which guarantees that the product will work in the applications and species specified on the datasheet, or we will offer a replacement, credit, or refund within 6 months of purchase.

I hope this information is helpful. Please do not hesitate to contact us again with any other questions.

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Answer

Thank you for contacting us.

We have the following products that may be of interest:

ab48960
West Nile Virus (E protein) protein (His tag)
www.abcam.com/ab48960
Recombinant fusion protein; West Nile Virus Envelope protein, N-terminal part of the Envelope protein, immunodominant region. Molecular weight ˜18kDa.
Expressed in E.coli

ab49049
West Nile Virus preM protein
www.abcam.com/ab49049
N-terminal region of the West Nile Virus Pre-M antigen (immunodominant region), with six histidines included.
Expressed in E.coli

I hope this information helps. Just let me know if you have further questions.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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