Key features and details
- Endogenous antioxidant
- CAS Number: 70-18-8
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameReduced Glutathione (GSH), Endogenous antioxidant
Endogenous antioxidant. Scavenger of hydroxyl radicals, reduces ROS. Forms disulfide bonds with cysteine residues of proteins. Protects against toxicity and disease. Weak inhibitor of glyoxalase I (Ki value = 18 mM). Active in vivo and in vitro.
SequenceXCG (Modifications: X-1 = Ggu)
Storage instructionsStore at -20°C. It is important to note that this is air sensitive and impurities can occur as a result of air oxidation. Store under desiccating conditions.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142044 has been referenced in 1 publication.
- Ghoneim FM et al. The Protective Role of Prenatal Alpha Lipoic Acid Supplementation against Pancreatic Oxidative Damage in Offspring of Valproic Acid-Treated Rats: Histological and Molecular Study. Biology (Basel) 9:N/A (2020). PubMed: 32825436