Overview

  • Product name

  • Description

    Rabbit polyclonal to REEP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human REEP1 aa 101-201.
    Database link: Q9H902

  • Positive control

    • WB: Mouse gonadal tissue lysate. IHC-P: Human testis and brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Detects a band of approximately 22, 80 kDa (predicted molecular weight: 23, 22, 19, 16 kDa).
IHC-P 1/20 - 1/200.

Target

  • Function

    May enhance the cell surface expression of odorant receptors.
  • Involvement in disease

    Defects in REEP1 are the cause of spastic paraplegia autosomal dominant type 31 (SPG31) [MIM:610250]. Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body.
  • Sequence similarities

    Belongs to the DP1 family.
  • Cellular localization

    Mitochondrion membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C2orf23 antibody
    • Chromosome 2 open reading frame 23 antibody
    • FLJ13110 antibody
    • Receptor accessory protein 1 antibody
    • Receptor expression-enhancing protein 1 antibody
    • Reep1 antibody
    • REEP1_HUMAN antibody
    • SPG31 antibody
    see all

Images

  • Anti-REEP1 antibody (ab230026) at 1/1000 dilution + Mouse gonadal tissue lysate

    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution

    Developed using the ECL technique.

    Predicted band size: 23, 22, 19, 16 kDa
    Observed band size: 22,80 kDa
    why is the actual band size different from the predicted?

  • Paraffin-embedded human testis tissue stained for REEP1 with ab230026 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human brain tissue stained for REEP1 with ab230026 at 1/100 dilution in immunohistochemical analysis.

References

ab230026 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230026.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up