Key features and details
- Rabbit polyclonal to REEP1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-REEP1 antibody
See all REEP1 primary antibodies
DescriptionRabbit polyclonal to REEP1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment corresponding to Human REEP1 aa 101-201.
Database link: Q9H902
- WB: Mouse gonadal tissue lysate. IHC-P: Human testis and brain tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab230026 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Detects a band of approximately 22, 80 kDa (predicted molecular weight: 23, 22, 19, 16 kDa).|
|IHC-P||1/20 - 1/200.|
FunctionMay enhance the cell surface expression of odorant receptors.
Involvement in diseaseDefects in REEP1 are the cause of spastic paraplegia autosomal dominant type 31 (SPG31) [MIM:610250]. Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body.
Sequence similaritiesBelongs to the DP1 family.
Cellular localizationMitochondrion membrane.
- Information by UniProt
- C2orf23 antibody
- Chromosome 2 open reading frame 23 antibody
- FLJ13110 antibody
Anti-REEP1 antibody (ab230026) at 1/1000 dilution + Mouse gonadal tissue lysate
Goat polyclonal to rabbit IgG at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 23, 22, 19, 16 kDa
Observed band size: 22,80 kDa why is the actual band size different from the predicted?
Paraffin-embedded human testis tissue stained for REEP1 with ab230026 at 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human brain tissue stained for REEP1 with ab230026 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230026 has not yet been referenced specifically in any publications.