Anti-REG3G antibody (ab198216)
Key features and details
- Rabbit polyclonal to REG3G
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-REG3G antibody
See all REG3G primary antibodies -
Description
Rabbit polyclonal to REG3G -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P HumanWB Human
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Immunogen
Fusion protein corresponding to Human REG3G (internal sequence). Fusion protein corresponding to a region derived from internal residues of human REG3G. The identity of the protein fusion partner is GST.
Database link: Q6UW15 -
Positive control
- WB: Human brain malignant glioma, mouse kidney and human kidney tissue lysates. IHC-P: Human colon cancer tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab198216 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Human
|
| WB |
Human
|
| All applications |
Rat
|
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/40 - 1/200.
|
|
| WB |
1/250 - 1/2000. Predicted molecular weight: 19 kDa.
|
| Notes |
|---|
|
IHC-P
1/40 - 1/200. |
|
WB
1/250 - 1/2000. Predicted molecular weight: 19 kDa. |
Target
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Function
Might be a stress protein involved in the control of bacterial proliferation. -
Tissue specificity
Expressed almost exclusively in the pancreas. Also expressed in testis. Not found in small intestine. -
Sequence similarities
Contains 1 C-type lectin domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 130120 Human
- Entrez Gene: 19695 Mouse
- Entrez Gene: 24620 Rat
- Omim: 609933 Human
- SwissProt: Q6UW15 Human
- SwissProt: O09049 Mouse
- SwissProt: P42854 Rat
- Unigene: 447084 Human
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Alternative names
- LPPM429 antibody
- Pancreatitis-associated protein 1B antibody
- Pancreatitis-associated protein IB antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG3G antibody (ab198216)
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue labeling REG3G with ab198216 at 1/40 dilution.
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Western blot - Anti-REG3G antibody (ab198216)All lanes : Anti-REG3G antibody (ab198216) at 1/250 dilution
Lane 1 : Human brain malignant glioma lysate
Lane 2 : Mouse kidney tissue lysate
Lane 3 : Human kidney tissue lysate
Lysates/proteins at 40 µg per lane.
Developed using the ECL technique.
Predicted band size: 19 kDa
Exposure time: 20 seconds
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab198216 has been referenced in 6 publications.
- Xiao Y et al. Interleukin-33 Promotes REG3? Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota. Cell Mol Gastroenterol Hepatol 8:21-36 (2019). PubMed: 30831322
- Berkowitz L et al. Mucosal Exposure to Cigarette Components Induces Intestinal Inflammation and Alters Antimicrobial Response in Mice. Front Immunol 10:2289 (2019). PubMed: 31608070
- Miyata T et al. CXCL12 expression in intrahepatic cholangiocarcinoma is associated with metastasis and poor prognosis. Cancer Sci 110:3197-3203 (2019). PubMed: 31361379
- Peng W et al. Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development. Mol Cell Biol 38:N/A (2018). PubMed: 29133460
- Wang J et al. Aryl hydrocarbon receptor/IL-22/Stat3 signaling pathway is involved in the modulation of intestinal mucosa antimicrobial molecules by commensal microbiota in mice. Innate Immun 24:297-306 (2018). PubMed: 29976114
- Chen L et al. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol 18:541-551 (2017). PubMed: 28288099