Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)
Key features and details
- Rabbit polyclonal to Relaxin 3 receptor 1 - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Relaxin 3 receptor 1 antibody - C-terminal
See all Relaxin 3 receptor 1 primary antibodies -
Description
Rabbit polyclonal to Relaxin 3 receptor 1 - C-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Hamster, Cow, Pig, Monkey, Gorilla, Common marmoset, Elephant
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Immunogen
Synthetic 17 amino acid peptide from the C terminus of Human GPCR SALPR.
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Positive control
- Human brain, neurons and glia.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140917 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 6 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| Notes |
|---|
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IHC-P
Use a concentration of 6 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. -
Tissue specificity
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 100406423 Common marmoset
- Entrez Gene: 539509 Cow
- Entrez Gene: 101149843 Gorilla
- Entrez Gene: 101841372 Hamster
- Entrez Gene: 51289 Human
- Entrez Gene: 239336 Mouse
- Entrez Gene: 100512567 Pig
- Entrez Gene: 294807 Rat
see all -
Alternative names
- G protein coupled receptor GPCR135 antibody
- G protein coupled receptor SALPR antibody
- G protein-coupled receptor SALPR antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons and glia labelling GPCR SALPR with ab140917 at 15 µg/ml.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab140917 has not yet been referenced specifically in any publications.