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Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)

    Key features and details

    • Rabbit polyclonal to Relaxin 3 receptor 1 - C-terminal
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

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    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-Relaxin 3 receptor 1 antibody - C-terminal
      See all Relaxin 3 receptor 1 primary antibodies
    • Description

      Rabbit polyclonal to Relaxin 3 receptor 1 - C-terminal
    • Host species

      Rabbit
    • Specificity

      BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse, Rat, Rabbit, Hamster, Cow, Pig, Monkey, Gorilla, Common marmoset, Elephant
    • Immunogen

      Synthetic 17 amino acid peptide from the C terminus of Human GPCR SALPR.

    • Positive control

      • Human brain, neurons and glia.
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C.
    • Storage buffer

      Preservative: 0.1% Sodium azide
      Constituent: 99% PBS
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmitter
      • Neuropeptides
      • Hormones
      • Signal Transduction
      • Signaling Pathway
      • G Protein Signaling
      • GPCR
      • Signal Transduction
      • Growth Factors/Hormones
      • Insulin / Insulin-like
      • Neuroscience
      • Neurology process
      • Metabolism
      • Neuroscience
      • Endocrine system
      • Gonadotrophic axis
      • Developmental Biology
      • Reproduction
      • Hormones

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab140917 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    Use a concentration of 6 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 6 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Target

    • Function

      Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
    • Tissue specificity

      Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession Q9NSD7 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 100406423 Common marmoset
      • Entrez Gene: 539509 Cow
      • Entrez Gene: 101149843 Gorilla
      • Entrez Gene: 101841372 Hamster
      • Entrez Gene: 51289 Human
      • Entrez Gene: 239336 Mouse
      • Entrez Gene: 100512567 Pig
      • Entrez Gene: 294807 Rat
      • Omim: 609445 Human
      • SwissProt: Q9NSD7 Human
      • SwissProt: Q8BGE9 Mouse
      • Unigene: 170146 Human
      • Unigene: 209312 Mouse
      • Unigene: 127658 Rat
      see all
    • Alternative names

      • G protein coupled receptor GPCR135 antibody
      • G protein coupled receptor SALPR antibody
      • G protein-coupled receptor SALPR antibody
      • G-protein coupled receptor GPCR135 antibody
      • GPCR 135 antibody
      • GPCR135 antibody
      • Gprotein coupled receptor SALPR antibody
      • Relaxin 3 receptor 1 antibody
      • Relaxin 3 receptor1 antibody
      • Relaxin 3/INSL7 receptor 1 antibody
      • Relaxin 3/INSL7 receptor1 antibody
      • Relaxin family peptide receptor 3 antibody
      • Relaxin family peptide receptor3 antibody
      • Relaxin-3 receptor 1 antibody
      • Relaxin/insulin like family peptide receptor 3 antibody
      • Relaxin3 receptor 1 antibody
      • Relaxin3 receptor1 antibody
      • RL3 R1 antibody
      • RL3R 1 antibody
      • RL3R1 antibody
      • RL3R1_HUMAN antibody
      • RLN3 receptor 1 antibody
      • RLN3 receptor1 antibody
      • RLN3R1 antibody
      • RXFP3 antibody
      • RXFPR3 antibody
      • SALP R antibody
      • SALPR antibody
      • somatostatin and angiotensin like peptide receptor antibody
      • Somatostatin- and angiotensin-like peptide receptor antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Relaxin 3 receptor 1 antibody - C-terminal (ab140917)
      Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons and glia labelling GPCR SALPR with ab140917 at 15 µg/ml.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab140917? Please let us know so that we can cite the reference in this datasheet.

    ab140917 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
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    Immunohistochemistry - Free Floating abreview for Anti-Relaxin 3 receptor 1 antibody - C-terminal

    Good
    Abreviews
    Abreviews
    abreview image
    Application
    Immunohistochemistry free floating
    Sample
    Mouse Tissue sections (Brain)
    Specification
    Brain
    Read More

    Dr. Hyun Jin Kim

    Verified customer

    Submitted Mar 21 2016

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