Renalase peptide (224-234) (ab45730)



  • Nature
  • Amino Acid Sequence
    • Species
    • Sequence
    • Amino acids
      224 to 234

Associated products


Our Abpromise guarantee covers the use of ab45730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Renalase antibody (ab31291)

  • Form
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • 6530404N21Rik
    • AI452315
    • AW060440
    • C10orf59
    • Chromosome 10 open reading frame 59
    • FLJ11218
    • HGNC:25641
    • Hypothetical protein LOC55328
    • MAO C
    • MAO-C
    • mMAO C
    • Monoamine oxidase C
    • Monoamine oxidase-C
    • Renalase
    • Renalase FAD dependent amine oxidase
    • RNLS
    see all
  • Function
    Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis (By similarity). According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity.
  • Tissue specificity
    Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects.
  • Sequence similarities
    Belongs to the renalase family.
  • Cellular localization
  • Information by UniProt


ab45730 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for contacting us.

As a suitable positive control for an anti-human renalase antibody, I would recommend the following product catalogue reference number ab134535 : Renalase protein (His tag),

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Thanks for your reply.

I think it will be very important, based on my knowledge of the situation, to get some specific details from the authors of the paper whose experiment you wish to reproduce. I suggest sending another email within a day ...

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Regarding your enquiry, I have spoken with my colleague John who you spoke with on August 9. He mentioned advising you to contact the authors of the study you are attempting to duplicate. I just wanted to know if you have heard from them yet ...

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Thank you for your email.

Yes, with the peptide you can make the standard curve.

When using unknown samples, you would just coat the well with the samples, but not the peptide. The peptide would be in separate wells. Also, try seve...

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Thank you for contacting us.

ELISA assay is used for determining the activity of the antibody by applying serially diluted antibody to micro-wells that are coated with the immunizing peptide. Please find below the protocol that was used, inc...

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Thank you for contacting Abcam about ab45730. I have contacted the lab to clarify what liquid the peptide, ab45730, is in and they have confirmed that unless otherwise stated, the peptide is in H2O. If there is anything else I can help yo...

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