Anti-DRAGON antibody (ab96727)
Key features and details
- Rabbit polyclonal to DRAGON
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DRAGON antibody
See all DRAGON primary antibodies -
Description
Rabbit polyclonal to DRAGON -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant fragment corresponding to Human DRAGON aa 219-467 (C terminal). NP_001012779
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Positive control
- 293T, HeLaS3, HepG2, Molt-4, Raji cell lysates. A431, H1299 whole cell lysates. U87 xenograft.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96727 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 52 kDa.
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IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 52 kDa. |
IHC-P
1/100 - 1/500. |
Target
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Function
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. -
Sequence similarities
Belongs to the repulsive guidance molecule (RGM) family. -
Post-translational
modificationsGPI-anchored. -
Cellular localization
Cell membrane. Membrane raft. - Information by UniProt
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Database links
- Entrez Gene: 285704 Human
- Entrez Gene: 68799 Mouse
- Omim: 612687 Human
- SwissProt: Q6NW40 Human
- SwissProt: Q7TQ33 Mouse
- Unigene: 526902 Human
- Unigene: 293466 Mouse
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Alternative names
- DRAGON antibody
- DRG11-responsive axonal guidance and outgrowth of neurite antibody
- Repulsive Guidance Molecule B antibody
see all
Images
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All lanes : Anti-DRAGON antibody (ab96727) at 1/1000 dilution
Lane 1 : A431 whole cell lysate
Lane 2 : H1299 whole cell lysate
Lane 3 : HeLa S3 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 52 kDa
10% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using ab96727 at 1/100 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab96727 has not yet been referenced specifically in any publications.