p65 post-translational modifications
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Explore post-translational modifications and their roles in p65 activation.
Post-translational modifications, including acetylation, phosphorylation, and methylation, determine the activation status of p65 . Find out where these modifications occur and whether they enhance or repress p65 transcriptional activity using the diagram below.
Figure 1. p65 post translational modifications. The locations of post-translational modifications are shown, along with the effect they have on p65 transcriptional activity. Click to expand image.
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| Modification | Amino acid | Recommended antibodies |
| Phosphorylation | T254 | ab131100 |
| S281 | ab193238 | |
| S311 | ab194926 | |
| T435 | ab194932, ab31472 | |
| S468 | ab194921 | |
| S529 | ab109458, ab47395 | |
| S536 | ab86299, ab76302 | |
| Acetylation | K310 | ab19870 |