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Published February 22, 2022
With the incidence of autoimmune diseases rising worldwide, research into translational immunology is becoming increasingly important, strengthening the demand for high-quality, specific biological reagents for research, drug discovery and diagnostics development.
Whether you’re trying to understand disease mechanisms, discover novel treatment strategies, or develop validated strategies for patient stratification for biologics treatments, we can support you with a broad, comprehensively validated portfolio covering key and emerging targets in autoimmune diseases.
Our autoimmune disease portfolio is aligned with three key therapeutic areas: rheumatology (eg, rheumatoid arthritis and lupus), gastroenterology (eg, inflammatory bowel disease), and dermatology (eg, psoriasis).
Key benefits of our autoimmune disease portfolio:
To ensure we continually develop our portfolio to meet the evolving needs of our customers, we work with an expert network of key opinion leaders who help us identify novel targets and emerging technologies to expand our range of high-quality reagents.
If a research tool you need is not available off the shelf, our in-house team of experts will work with you to create a customized solution.
We’re committed to covering all widely studied and emerging targets for autoimmune diseases, including:
Take advantage of our wide range of well-validated proteomic reagents for autoimmune disease research—from recombinant antibodies and ELISA kits to proteins and edited cell lines — with excellent batch-to-batch consistency and guaranteed long-term supply.
Investigate novel mechanistic and treatment targets in autoimmune diseases
More flexibility to characterize new cell populations via flow cytometry
Stimulate immune cells with bioactive cytokines and chemokines
Guaranteed long-term supply, confirmed specificity, and the highest level of consistency between batches.
Wide label coverage across the imaging spectrum to enable flexibility in panel building
Batch-to-batch consistent bioactive proteins suitable for functional studies and cell culture; a broad range of antigens for immunoassay development
|Recommended products for IBD research||Integrin beta 4 (ab182120)||APC Anti-GATA3 (ab225418)||IL-6 (ab259381)|
|Recommended products for rheumatology research||Interferon alpha/beta receptor 1 (ab124764)||CD74 carrier-free (ab289891)||TNF alpha (ab259410)|
|Recommended products for dermatology research||JAK3 (ab45141)||IL-23R carrier-free (ab255964)|
Autoimmune disease biomarkers are important for research, can serve as a diagnostic and are used to monitor the progress of drug therapy. See below our comprehensive portfolio of ELISA kits, antibody pairs, and FirePlex multiplex immunoassays for human samples to accelerate biomarker research in autoimmune diseases.
Human SimpleStep ELISA® kits
Human ELISA antibody pairs
Rapidly validate autoimmune disease biomarkers to stratify patients by disease severity
Develop your own ELISA assay
Simultaneously profile key inflammation markers
With just one wash step and no compromise in performance, our highly sensitive ELISA kits give you reliable results in 90 minutes.
High-performing matched antibody pairs allow you to achieve consistent, specific and sensitive results, while carrier-free formulations give you more flexibility in terms of conjugation and assay setup.
High-throughput no-wash automation-friendly immunoassays, ideal for discovery, screening, and profiling projects.
Common autoimmune markers
Immunoassay Panel 1 (ab234897): IL-8, IFN gamma, IL-4, IL-1 beta, MCP1, TNF alpha, IL-10, IL-17A, IL-2, IL-6
FirePlex®-96 Inflammation, Human Immunoassay Panel (ab243550): IFN gamma, IL-1 beta, IL-6, IL-8, IL-10, IL-12p70, MCP1, TNF alpha
FirePlex®-384 TGF-beta (Human, Mouse, Rat, NHP) Immunoassay Panel (ab270739) -TGF-B1, TGF-B2, and TGF-B3