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Home Epigenetics and Nuclear Signaling

Chromatin modifying enzymes

Product
  • Acetylation
  • ADP-ribosylation
  • Arginine Deiminases
  • Deamination
  • Jumonji containing proteins
  • Methylation
  • Phosphorylation
  • Sumoylation
  • Ubiquitylation

Also known as writers and erasers, these enzyme families add or remove epigenetic marks on histones. Notable examples include the polycomb complexes PRC1 and PRC2, which silence genes by tri-methylating H3K27 and mono-ubiquitinating H2AK119. Our resources include ChIP grade antibodies for chromatin modifiers, and HDAC/SIRT inhibitors and activity kits.

Browse all related products

Features

A guide to chromatin structure and function

Learn the basics of chromatin structure and function, and how to study chromatin using chromatin immunoprecipitation (ChIP).

ChIP 2.0 - advanced guide

Our advanced guide to ChIP covers some of the most advanced ChIP-based techniques, including ChIP-loop, ChIA-PET, ChIP-exo and ChIP-BS-seq.

Chromosome conformation capture (3C)

Discover our guide to chromosome conformation capture, summarizing current 3C methods and helping you to choose the best option for your lab.

ChIP antibodies

Discover our range of antibodies validated for ChIP, ChIP-chip and ChIP-seq, as well as ChIP protocols to guide you through your experiment.

  • All
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Immunoprecipitation protocol

Immunoprecipitation protocol

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Protocol

ChIP technique

Cross-linking chromatin immunoprecipitation (X-ChIP) protocol

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Protocol

A Step-by-Step Guide to ChIP-Seq Data Analysis

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Video

Protocols and troubleshooting tips, to help get the best from our antibodies

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Protocol

Secondary antibodies optimized for co-IP western blotting

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Article

Epigenetics guide

Epigenetic modifications poster

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Pathway

ChIP technique

Advances in ChIP-Seq analysis with small samples

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Article

Histone western blot protocol

638108562330000000

Protocol

ChIP technique

Native chromatin immunoprecipitation protocol

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Protocol

ChIP technique

Chromatin preparation from tissues for ChIP

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Protocol

Histone extraction protocol for western blot

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Protocol

ChIP troubleshooting tips

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Protocol

ChIP tips by Dr Andy Bannister of the Gurdon Institute

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Protocol

Chromatin and histone extraction kits

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Article

ChIP using plant samples - Arabidopsis

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Protocol

ChIP 2.0: Guide to advanced chromatin immunoprecipitation

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Article

ChIP and ChIP-seq kits: from high sensitivity to fast protocols.

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Article

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