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Chromatin modifying enzymes
Also known as writers and erasers, these enzyme families add or remove epigenetic marks on histones. Notable examples include the polycomb complexes PRC1 and PRC2, which silence genes by tri-methylating H3K27 and mono-ubiquitinating H2AK119. Our resources include ChIP grade antibodies for chromatin modifiers, and HDAC/SIRT inhibitors and activity kits.
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