Home Epigenetics and Nuclear Signaling

Chromatin modifying enzymes

Also known as writers and erasers, these enzyme families add or remove epigenetic marks on histones. Notable examples include the polycomb complexes PRC1 and PRC2, which silence genes by tri-methylating H3K27 and mono-ubiquitinating H2AK119. Our resources include ChIP grade antibodies for chromatin modifiers, and HDAC/SIRT inhibitors and activity kits.

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A guide to chromatin structure and function

Learn the basics of chromatin structure and function, and how to study chromatin using chromatin immunoprecipitation (ChIP).

ChIP 2.0 - advanced guide

Our advanced guide to ChIP covers some of the most advanced ChIP-based techniques, including ChIP-loop, ChIA-PET, ChIP-exo and ChIP-BS-seq.

Chromosome conformation capture (3C)

Discover our guide to chromosome conformation capture, summarizing current 3C methods and helping you to choose the best option for your lab.

ChIP antibodies

Discover our range of antibodies validated for ChIP, ChIP-chip and ChIP-seq, as well as ChIP protocols to guide you through your experiment.

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Epigenetics conference calendar

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A Beginner's Guide to ChIP

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ChIP troubleshooting tips

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Epigenetics round-up of 2014

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Immunoprecipitation protocol

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Applications of ChIP

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Histone western blot protocol

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Epigenetic modifications poster

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The Role of Polycombs in Cancer

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chip grade antibodies

Epigenetics glossary

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HDAC inhibitors

HDAC inhibitors

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HDAC/SIRT activity assays

HDAC & SIRT activity kits

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K27

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K4

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K9

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