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Home Epigenetics and Nuclear Signaling

Chromatin structure

Product
  • Centromeres
  • Chromatin assembly
  • Chromosome
  • Cohesins
  • Scaffold Proteins
  • Telomeres

DNA wraps around histones to form the nucleosome, the basic chromatin unit. Tightly packed heterochromatin forms structures such as telomeres and centromeres, whereas euchromatin features active genes. Chromatin immunoprecipitation (ChIP) is a popular application in the epigenetics field, and emerging techniques include 3C and derivatives. We provide antibodies and kits for chromatin extraction and ChIP.

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Features

A guide to chromatin structure and accessibility

Learn about chromatin structure, methods to study DNA accessibility and nucleosome positioning, and chromosome conformation techniques.

Epigenetics application spotlight: miCLIP

Learn the miCLIP basics, including protocol steps, advantages, and applications, and see the limitations of existing m6A detection methods.

​​​​Epigenetics application spotlight: ATAC-seq

See the detailed ATAC-seq protocol and learn more about this rapid and sensitive technique to assess genome-wide chromatin accessibility. 

​Evolution of chromosome conformation capture

See the evolution of chromosome conformation capture (3C) method, including innovation in 3C methods and the future of 3C.

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Epigenetics conference calendar

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Learn about miCLIP

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Learn about ATAC-seq

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Epigenetic mechanisms webinar-

Epigenetic Mechanisms in Early Mammalian Development

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Video

Applications of ChIP

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Video

A Beginner's Guide to ChIP

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Video

Immunoprecipitation protocol

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Protocol

Histone western blot protocol

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Protocol

ChIP tips by Dr Andy Bannister of the Gurdon Institute

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Protocol

ChIP troubleshooting tips

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Protocol

Getting started with Chromatin Conformation Capture (3C)

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Article

Chromatin preparation from tissues for ChIP

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Protocol

Chromatin and histone extraction kits

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Article

A Step-by-Step Guide to ChIP-Seq Data Analysis

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Video

ChIP using plant samples - Arabidopsis

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Protocol

Introduction to ChIP Principles with Troubleshooting Tips

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Video

ChIP 2.0: Guide to advanced chromatin immunoprecipitation

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Article

Beyond ChIP Studies: the evolution of chromosome conformation capture

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Epigenetic modifications poster

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Pathway

Advances in ChIP-Seq analysis with small samples

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ChIP and ChIP-seq kits: from high sensitivity to fast protocols.

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Native chromatin immunoprecipitation protocol

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Protocol

Cross-linking chromatin immunoprecipitation (X-ChIP) protocol

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Protocol

Histone extraction protocol for western blot

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Protocol

Chromatin accessibility and architecture

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chip grade antibodies

Browse over 600 ChIP grade antibodies

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Histone acetyltransferase activity assay kit

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HDAC inhibitors

HDAC inhibitors

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HDAC/SIRT activity assays

HDAC & SIRT activity kits

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K27

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K4

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Histone H3 ChIP-grade antibodies

ChIP-grade antibodies to H3K9

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