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Home Epigenetics and Nuclear Signaling

Chromatin structure

Product
  • Centromeres
  • Chromatin assembly
  • Chromosome
  • Cohesins
  • Scaffold Proteins
  • Telomeres

DNA wraps around histones to form the nucleosome, the basic chromatin unit. Tightly packed heterochromatin forms structures such as telomeres and centromeres, whereas euchromatin features active genes. Chromatin immunoprecipitation (ChIP) is a popular application in the epigenetics field, and emerging techniques include 3C and derivatives. We provide antibodies and kits for chromatin extraction and ChIP.

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Features

A guide to chromatin structure and accessibility

Learn about chromatin structure, methods to study DNA accessibility and nucleosome positioning, and chromosome conformation techniques.

Epigenetics application spotlight: miCLIP

Learn the miCLIP basics, including protocol steps, advantages, and applications, and see the limitations of existing m6A detection methods.

​​​​Epigenetics application spotlight: ATAC-seq

See the detailed ATAC-seq protocol and learn more about this rapid and sensitive technique to assess genome-wide chromatin accessibility. 

​Evolution of chromosome conformation capture

See the evolution of chromosome conformation capture (3C) method, including innovation in 3C methods and the future of 3C.

  • All
  • Articles
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Introduction to ChIP Principles with Troubleshooting Tips

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Video

Immunoprecipitation protocol

637806879100000000

Protocol

Advances in ChIP-Seq analysis with small samples

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Article

Histone extraction protocol for western blot

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Protocol

Chromatin accessibility and architecture

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Article

Cross-linking chromatin immunoprecipitation (X-ChIP) protocol

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Protocol

A Beginner's Guide to ChIP

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Video

A Step-by-Step Guide to ChIP-Seq Data Analysis

637648855970000000

Video

Native chromatin immunoprecipitation protocol

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Protocol

ChIP troubleshooting tips

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Protocol

Chromatin preparation from tissues for ChIP

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Protocol

ChIP tips by Dr Andy Bannister of the Gurdon Institute

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Protocol

Histone western blot protocol

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Protocol

Epigenetic modifications poster

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Pathway

Chromatin and histone extraction kits

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Article

Epigenetic mechanisms webinar-

Epigenetic Mechanisms in Early Mammalian Development

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Video

Applications of ChIP

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Video

ChIP using plant samples - Arabidopsis

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Protocol

ChIP 2.0: Guide to advanced chromatin immunoprecipitation

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Article

Beyond ChIP Studies: the evolution of chromosome conformation capture

637493396280000000

Article

ChIP and ChIP-seq kits: from high sensitivity to fast protocols.

637486545250000000

Article

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