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Nuclear signaling pathways

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Signaling pathways trigger specific gene expression programs via transcription factors. This happens in response to receptor-ligand interactions either on the nuclear or cellular membrane. Our resources for nuclear signaling research covers pathways including NF-kB, JAK-STAT, TGF​β/SMAD and NFAT. Explore our related resources and products below.

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Features

NF-κB signaling pathway

Review the pathways that result in canonical and non-canonical ​​​​​NF-κB activation and downstream gene expression.

Scientific pathway poster library

Discover over 70 of our scientific posters covering all research areas and download a PDF or request a hard copy for your lab.

Interactive pathways

Our interactive pathways are a collection of major biological pathways designed to help you find high quality products for your particular area of research.


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NF-κB interactive pathway

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Pathway

Calcium signaling interactive pathway

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Pathway

Protocols and troubleshooting tips, to help get the best from our antibodies

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Protocol

Methods to study transcription factor activation

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Article

TGF-beta/Smad interactive pathway

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Pathway

ERK1/2 signaling in cancer

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Article

p65 and the NF-kB inflammatory pathway

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Article

Overview of NF-κB signaling

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Article

Hedgehog signaling pathway: an overview

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Article