For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome

Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online
United States
Your country/region is currently set to:

If incorrect, please enter your country/region into the box below, to view site information related to your country/region.

Call (888) 77-ABCAM (22226) or contact us
Need help? Contact us

  • My account
  • Sign out
Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us
My basket
Quick order
Abcam homepage

  • Research Products
    By product type
    Primary antibodies
    Secondary antibodies
    ELISA and Matched Antibody Pair Kits
    Cell and tissue imaging tools
    Cellular and biochemical assays
    Proteins and Peptides
    By product type
    Proteomics tools
    Agonists, activators, antagonists and inhibitors
    Cell lines and Lysates
    Multiplex miRNA assays
    Multiplex Assays
    By research area
    Cancer
    Cardiovascular
    Cell Biology
    Epigenetics
    Metabolism
    Developmental Biology
    By research area
    Immunology
    Microbiology
    Neuroscience
    Signal Transduction
    Stem Cells
  • Customized Products & Partnerships
    Customized Products & Partnerships

    Customized products and commercial partnerships to accelerate your diagnostic and therapeutic programs.

    Customized products

    Partner with us

  • Support
    Support hub

    Access advice and support for any research roadblock

    View support hub

    Protocols

    Your experiments laid out step by step

    View protocols

  • Events
    • Conference calendar
    • Cancer
    • Cardiovascular
    • Epigenetics & Nuclear signaling
    • Immunology
    • Neuroscience
    • Stem cells
    • Tradeshows
    • Scientific webinars
    Keep up to date with the latest events

    Full event breakdown with abstracts, speakers, registration and more

    View global event calendar

  • Pathways
    Cell signalling pathways

    View all pathways

    View all interactive pathways

Home Epigenetics and Nuclear Signaling

Transcription

Product
  • Bromodomain containing
  • Cancer susceptibility
  • Co-factors
  • Domain Families
  • Elongation factors
  • Krueppel like factor
  • Mediator Complex
  • Polymerase associated factors
  • Preinitiation complex
  • RNA polymerase
  • Transcription Factors

Transcription factors control gene expression by binding promoters and enhancers on DNA. Factors such as c-Myc are mutated in many cancers, while others including Sox2 and Nanog are critical for stem cell pluripotency. Our tools for transcription research include antibodies and transcription factor binding assays. Find out more with the resources below.

Browse all related products

Features

Transcription factor binding assay kits

Measure the DNA binding activity of specific transcription factors with our assay kits.

​Sox2 antibodies

Antibodies to Sox2, validated in applications including ChIP, flow cytometry, IHC, immunoprecipitation and western blot.

​​​Nanog antibodies

Antibodies to Nanog, validated in applications including ChIP, flow cytometry, IHC, immunoprecipitation and western blot.

An overview of c-Myc

An overview of the structure, function and regulation of the c-Myc protein.

  • All
  • Articles
  • Event
  • Protocols
  • Videos

Introduction to ChIP Principles with Troubleshooting Tips

637807118480000000

Video

Immunoprecipitation protocol

637806879100000000

Protocol

Advances in ChIP-Seq analysis with small samples

637806855890000000

Article

Secondary antibodies optimized for co-IP western blotting

637725641120000000

Article

Epigenetics conference calendar

637720657570000000

Event

Protocols and troubleshooting tips, to help get the best from our antibodies

637715291520000000

Protocol

A Beginner's Guide to ChIP

637653301730000000

Video

ChIP troubleshooting tips

637648845800000000

Protocol

ChIP tips by Dr Andy Bannister of the Gurdon Institute

637648834050000000

Protocol

rnaseqwebinar212x70

Single Cell RNA-Seq and Cell Heterogeneity in the Central Nervous System

637496002980000000

Video

Epigenetic mechanisms webinar-

Epigenetic Mechanisms in Early Mammalian Development

637493458900000000

Video

Applications of ChIP

637493458060000000

Video

ChIP 2.0: Guide to advanced chromatin immunoprecipitation

637493397470000000

Article

ChIP and ChIP-seq kits: from high sensitivity to fast protocols.

637486545250000000

Article

Methods to study transcription factor activation

637383263740000000

Article

Get resources and offers direct to your inbox Sign up
A-Z by research area
  • Cancer
  • Cardiovascular
  • Cell biology
  • Developmental biology
  • Epigenetics & Nuclear signaling
  • Immunology
  • Metabolism
  • Microbiology
  • Neuroscience
  • Signal transduction
  • Stem cells
A-Z by product type
  • Primary antibodies
  • Secondary antibodies
  • Biochemicals
  • Isotype controls
  • Flow cytometry multi-color selector
  • Kits
  • Loading controls
  • Lysates
  • Peptides
  • Proteins
  • Slides
  • Tags and cell markers
  • Tools & Reagents
Help & support
  • Support
  • Make an Inquiry
  • Protocols & troubleshooting
  • Placing an order
  • RabMAb products
  • Biochemical product FAQs
  • Training
  • Browse by Target
Company
  • Corporate site
  • Investor relations
  • Company news
  • Careers
  • About us
  • Blog
Events
  • Tradeshows
  • Conferences
International websites
  • abcam.cn
  • abcam.co.jp

Join with us

  • LinkedIn
  • facebook
  • Twitter
  • YouTube
  • Terms of sale
  • Website terms of use
  • Cookie policy
  • Privacy policy
  • Legal
  • Modern slavery statement
© 1998-2022 Abcam plc. All rights reserved.