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Ubiquitination is a post-translational modification in which ubiquitin is covalently attached to target proteins via an enzymatic cascade comprising E1s, E2s, E3s. We offer on increasing range tools for the field including recombinant ubiquitin, ubiquitin activating and conjugating enzymes, ubiquitin ligases, deubiquitinases and other reagents.
Our ubiquitin chains poster summarizes the ubiquitylation cascade, ubiquitin linkages bound to substrate proteins and their diverse functions in vivo.
Ubiquitin is involved with a wide variety of cellular processes. Discover more about ubiquitin, including our range of products and ubiquitination protocol.